Research Dosing

Tesamorelin

🔴 IMPORTANT: Read This Before Proceeding With Dosing
Go to the Prep & Injection Guide for proper reconstitution, syringe sizing, and injection protocols. Mistakes here can compromise your research.

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Tesamorelin

Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) that stimulates the release of human growth hormone (HGH). FDA-approved for body fat redistribution syndrome, Tesamorelin has shown powerful effects on fat loss, muscle preservation, nerve regeneration, and cognitive enhancement.

It is not a steroid and does not affect testosterone levels.

Benefits

  • Reduces adipose fat tissue (especially in the abdomen and upper back)
  • Targets visceral fat around internal organs (liver, stomach, intestines)
  • Preserves and increases lean muscle mass
  • Boosts metabolism and energy output
  • Reduces cholesterol and triglycerides
  • Supports nerve regeneration after injury
  • Increases neurotransmitters tied to cognitive performance

Possible Side Effects

  • Injection site irritation (redness, swelling, itching)
  • Muscle aches and pain
  • Headache
  • Nausea
  • Diarrhea
  • Sweating
  • Carpal tunnel symptoms
  • Edema
  • Fluid retention

Rare but More Serious Side Effects

  • Diarrhea with fever and dehydration
  • Shortness of breath
  • Joint or muscle pain
  • Numbness or tingling in the extremities
  • May increase risk of Type-2 diabetes

Interactions

Tirzepatide and Tesamorelin should only be used together under close medical supervision for diabetics, due to the fact that they have opposing effects on blood glucose levels, which may reduce the effectiveness of diabetes management. Tesamorelin tends to raise blood sugar, while tirzepatide lowers it, potentially leading to unpredictable glucose control. In addition to the concerns regarding diabetics, taking Tesamorelin with Tirzepatide may make the Tirzepatide less effective.

Contraindications

Do not use Tesamorelin if:

  • You’ve had pituitary tumors or surgery
  • You have an active malignancy
  • You’re allergic to mannitol
  • You’re pregnant or breastfeeding
  • You’ve had hypothalamic-pituitary axis disruption
  • You have a diagnosed pituitary disorder

Reconstitution and Dosing

12-16 week cycle followed by a 4-8 week washout
Inject 5 days per week with 2 consecutive rest days
Dose at night, at least 90 minutes after your last meal

Subcutaneous Administration

TESAMORELIN: 10MG

Mix with 2.5mL (250 units) of BAC water

Standard Protocol

25 units (1mg), 1x/day, 5 days/week

Maximum Protocol

50 units (2mg), 1x/day, 5 days/ week

TESAMORELIN: 20MG

Mix with 3mL (300 units) of BAC water

Standard Protocol

15 units (1mg), 1x/day, 5 days/week

Maximum Protocol

30 units (2mg), 1x/day, 5 days/week

Stacking Suggestions

Tesamorelin stacks extremely well with other fat-burning and GH-boosting peptides:

  • AOD-9604 – Targeted fat burning, especially abdominal
  • CJC-1295 / Ipamorelin – Synergistic GH elevation for deeper fat loss and muscle growth
  • GHK-Cu – Tissue regeneration and skin improvement
  • MOTS-C – Boosts metabolic performance and ATP levels
  • SS-31 – Mitochondrial repair and enhanced nerve healing
  • L-Carnitine – Enhances fat metabolism during GH therapy

Fat loss stack: Tesamorelin + AOD-9604 + CJC-1295
Neuroregeneration stack: Tesamorelin + SS-31 + MOTS-C
Aesthetic stack: Tesamorelin + GHK-Cu + CJC-1295